HLA Profile and Clinical Presentation of Multiple Sclerosis in Iran
نویسندگان
1 Professor of Neurology,Shahid Beheshti University of Medical Sciences
2 Assistant Professor of Neurology, Jundishapoor University of Medical Sciences
doi
10.22037/ijcn.v2i1.467چکیده
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system,with unknown etiology in which both genetic and environmental factors are thought to be involved. The HLA system provides a set of genetic markers which lend themselves to systematic study. The disease also has variable clinical manifestations, ranging from a relapsing-remitting course to a chronic progressive disease.In this article we review HLA profile and clinical presentation of the disease from current available data in Iran.