The Effect of Induced Hyperglycemia (Diabetes Type 1) on the mRNA Level of Toll-Like Receptor 4 Gene in the Diabetic Heart of Wistar Rats.

نویسندگان

1 Immunology Section, Department Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad-Iran. Biotechnology Section, Department of Pathology, Faculty of Veterinary Medicine, Ferdowsi University of Maashhad, Mashhad-Iran.

2 Immunology Section, Department Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad-Iran. Biotechnology Section, Department of Pathology, Faculty of Veterinary Medicine, Ferdowsi University of Maashhad, Mashhad-Iran.

3 Yazd Cardiovascular Research Center, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad-Iran.

4 Department of Biology, Faculty of Science, Isfahan University, Isfahan, Iran.

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چکیده

Abstract Objective: The previous studies indicated that the TLRs especially Toll-like receptor 4) TLR4 (are involved in the process of diabetes. The aim of the present research was to investigate the time course expression pattern of TLR4-a main component of innate immune system- in mRNA levels in the heart tissue ...