The Effect of High-Intensity Interval Training on Apoptotic-Related Genes in Skeletal Muscle and Serumic TNF-Alpha of Diabetic Rats

نویسندگان

1 Associate Professor, Department of Exercise Physiology, Faculty of Physical Education, Kharazmi University, Tehran, Iran.

2 PhD Student in Kinesiology, The University of Laval, Quebec, Canada.

3 MSc Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education, Kharazmi University, Tehran, Iran.

doi
10.18502/ijdo.v15i1.12212
چکیده

Objective: Diabetes is characterized by a comprehensive increase in apoptosis, mitochondrial dysfunction, and inflammation in skeletal muscle. Impaired mitochondrial function in skeletal muscle leads to an increase in Cytochrome C and Caspase-9, and muscle performance is reduced consequently. Exercise training through decreasing inflammatory factors and increasing anti-inflammatory elements prevents apoptosis pathways. Materials ...