Impact of High-Intensity Interval Training on GLP-1R/ PKBα Axis in Pancreatic Tissue of Diabetic Rats Induced by High-Fat Diet and STZ

نویسندگان

1 Assistant Professor of Exercise Physiology, Islamshahr Branch, Islamic Azad University, Tehran, Iran.

2 PHD Candidate, Department of Exercise Physiology, Islamshahr Branch, Islamic Azad University, Tehran, Iran.

3 Assistant professor of Exercise Physiology, Saveh Branch, Islamic Azad University, Saveh, Iran

4 Assistant professor of Exercise Physiology, Islamshahr Branch, Islamic Azad University, Tehran, Iran

5 Assistant Professor of Exercise Physiology, Islamshahr Branch, Islamic Azad University, Tehran, Iran.

doi
10.18502/ijdo.v15i4.14553
چکیده

Objective: Apart from hormonal factors and oxidative stress, insulin synthesis is strongly dependent on transcription factors in the pancreas. The aim of the present study was to assess the impact of high-intensity interval training (HIIT) on genes affecting insulin synthesis in diabetic obese rats. Materials and Methods: Type 2 diabetes (T2D) ...