Correlation between Cytochrome P450, 5-alpha Reductase, and Androgen Receptor Levels in Patients with Type 2 Diabetes Mellitus

نویسندگان
Homayouni Tabrizi, Masoud ID 1
Pouresmaeil, Vahid ID 2
Aljanabi, Mustafa Ali Hasan ID 3

1 Department of Biochemistry, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.

2 Department of Biochemistry, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.Innovative Medical Research Center, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.

3 Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

doi
10.18502/ijdo.v14i1.8738
چکیده

Objective: Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases. The CYP450 plays an important role in the biosynthesis of steroid hormones and the hormonal activity is mediated by the androgen receptor (AR) and the enzyme 5-alpha reductase (5αR). Therefore, this study aimed to investigate the relationship ...

کلیدواژه‌ها
Diabetes mellitus, Cytochrome P450, 5-alpha reductase, Androgen receptor