The Effects of Adding Spironolactone to ACEI or ARB on Proteinuria in Type 2 Diabetes
نویسندگان
1 Resident of internal medicine, Division of Nephrology, Department of Internal Medicine, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
2 Assistant Professor Division of Nephrology, Yazd Diabetes Research Center, Yazd. Iran
3 Assistant Professor of Endocrinology, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
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چکیده
Abstract Objectives: Interruption of rennin-angiotensin-aldosterone system has become a leading therapeutic strategy in the treatment of diabetic nephropathy however, ACEIs and ARBs do not uniformly suppress the rennin-angiotensin-aldosterone system. Plasma aldosterone levels are elevated in a group of patients despite therapy and this phenomenon known as aldosterone escape or aldosterone break through. ...
