Anti-Inflammatory Effects of Atorvastatin by the Modulation of NF-κB Expression during Hyperglycemia-Induced Nephropathy in Rat
نویسندگان
1 Department of Physiology and Biophysics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
2 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
3 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
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چکیده
Objective: Atorvastatin has the pleiotropic effects, including anti-inflammation and antioxidant. Therefore, this study considered to examine the effects of atorvastatin on NF-қB expression, as a main transcription factor for expression of inflammatory cytokines, in hyperglycemia-induced nephropathy in rat. Materials and Methods: Twenty four male Wistar rats were randomly divided into four ...
