Simultaneous Effects of Metformin and Sitagliptin on the Contents of Insulin Resistance Proteins Glucose Transporter 4 and Protein Kinase B in Diabetic Patients' Adipose Tissue

نویسندگان

1 Department of General Surgery, Faculty of Medicine, Shahid Saduoghi University of Medical Sciences, Yazd, Iran.

2 Diabetes Research Center, Shahid Saduoghi University of Medical Sciences, Yazd, Iran.

3 Department of Biochemistry and Molecular Biology, Faculty of Medicine, International Campus Of Shahid Saduoghi University of Medical Sciences, Yazd, Iran. Department of Biochemistry, Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran.

4 Department of Biochemistry and Molecular Biology, Faculty of Medicine, Shahid Saduoghi University of Medical Sciences, Yazd, Iran.

5 Department of Biochemistry and Molecular Biology, Faculty of Medicine, Shahid Saduoghi University of Medical Sciences, Yazd, Iran

doi
10.18502/ijdo.v13i2.6479
چکیده

Objective: Obesity is a factor in the development of insulin resistance and type 2 diabetes. Obesity contributes a wide variety of metabolic changes such as insulin resistance. The insulin signal mechanism to intra-cells occurs in insulin resistance, primarily in adipose tissue cells, which can be appropriate targets for therapeutic approaches by recognizing the ...