Side effects of hydroxyurea in patients with Thalassemia major and thalassemia intermedia and sickle cell anemia
نویسندگان
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چکیده
Background Sickle hemoglobin is the most common abnormal hemoglobin in the United States. Hemoglobin S arises as a result of a single amino acid substitution (glutamic acid to valin at position 6 of the β-globine chain). The presence of fetal hemoglobin (HbF) plays a relatively protective role since a significant amount of HbF interferes with HbS ...
