Low Frequency of C-MPL Gene Mutations in Iranian Patients with Philadelphia-Negative Myeloproliferative Disorders

نویسندگان
Ghasemi, A. ID 1
Abbasian, S ID 2
Rostami, S ID 3
Ghotaslou, A ID 4
Nadali, F ID 5
Chahardouli, B ID 6

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چکیده

Background Myeloproliferative disorders are a group of diseases characterized by increased proliferation of myeloid lineage. In addition to JAK2V617F mutation, several mutations in the c-MPL gene were described in patients with Philadelphia-negative chronic myeloproliferative disorders that could be important in the pathogenesis of diseases. The aim of present study was to ...

کلیدواژه‌ها
ARMS –PCR, c- MPL mutation, JAK2V617F, Myeloproliferative Disorders