Therapeutic approaches in patients with β-thalassemia
نویسندگان
1 Department of Hematology, faculty of paramedical, Birjand University of Medical Science, Birjand, Iran
2 Department of Medical Biotechnology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
3 Cardiovascular Diseases Research Center, Department of molecular medicine, Birjand University of Medical Sciences, Birjand, Iran
doi
10.18502/ijpho.v12i1.8364چکیده
Beta-thalassemia (β-thal) is a congenital hemoglobinopathy explained by a decreased level (β+) or absence (βο) of β-globin gene expression. Microcytic hypochromic anemia and various clinical symptoms comprising severe anemia to clinically nonsymptomatic features. Treatment with an ordered blood transfusion and iron chelator agents can decrease transfusion iron overload that causes normal maturation. ...
