Hemophagocytic lymphohistiocytosis secondary to T-cell Acute Lymphoblastic Leukemia with membranous tonsillitis

نویسندگان

1 Department of Paediatrics, Lady Hardinge Medical College & Associated SSK and KSC Hospitals, New Delhi

2 Department of Pathology, Lady Hardinge Medical College & Associated SSK and KSC Hospitals, New Delhi

3 Department of Pathology, Lady Hardinge Medical College & Associated SSK and KSC Hospitals, New Delhi

4 Department of Pathology, Lady Hardinge Medical College & Associated SSK and KSC Hospitals, New Delhi

doi
10.18502/ijpho.v12i4.10919
چکیده

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of excessive immune activation, which is characterized by fever, hepatosplenomegaly, cytopenias, hyperferritinemia, hypertriglyceridemia, and/or hypofibrinogenemia, and evidence of hemophagocytosis. Secondary HLH is often seen in adults and categorized based on autoimmune, infections-related, and malignancy-associated etiologies such as A-HLH, I-HLH, and M-HLH, respectively. This study ...