The frequency of PAX3 and PAX7 Mutations in Children with Rhabdomyosarcoma

نویسندگان
Jadali , Farzaneh ID 1
Goudarzi Pour , Kourosh ID 2
Ahmadi, Mehran Arab ID 3
Aghakhani, Roxana ID 4
Khoddami , Maliheh ID 5
Behnam , Behdad ID 6

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چکیده

Abstract Background: Rhabdomyosarcoma is the most common soft tissue sarcoma among children which has two major subtypes: embryonal rhabdomyosarcoma (ERMS) and alveolar rhabdomyosarcoma (ARMS). Distinction between these subtypes is mandatory to choose proper treatment and to determine prognosis. Histopathologic study is the main method, but nowadays molecular studies like PCR ...

کلیدواژه‌ها
Key words: Children, Histopathology, PAX-3, PAX-7, Rhabdomyosarcoma