CAR T-cell Therapy of Hematologic Malignancies: An Update in Targeted Antigens
نویسندگان
1 Department of Laboratory Science, Young Researchers and Elites Club, Gorgan Branch, Islamic Azad University, Gorgan, Iran
2 Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3 Department of Applied Cell Sciences, Faaculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran
doi
10.18502/ijpho.v13i2.12343چکیده
Immunotherapy with genetically engineered T-cells that express the chimeric antigen receptor (CAR) has raised hopes for the treatment of pediatric malignancies. Although CAR T-cell development is on a fast-moving pace and evolution, the context of exploring novel targetable antigens has been neglected. In this review study, we analyze the prominent hematologic ...
