Relationship between Molecular Chimerism and Graft Versus Host Disease after Allogenic Hematopoietic Stem Cell Transplantation

نویسندگان

1 Qaem Hospital, Mashhad University of Medical Science, Mashhad, Iran

2 Department of Hematology, School of Allied Medical Sciences, IRAN University of Medical Sciences, Tehran, IRAN.

3 Resident of Pathology, Cancer Molecular Pathology Research Center, Mashhad University of Medical Science, Mashhad, Iran.

4 Radiologist, Cancer Molecular Pathology Research Center, Mashhad University of Medical Science, Mashhad, IRAN.

5 Resident of Pathology, Cancer Molecular Pathology Research Center, Mashhad University of Medical Science, Mashhad, Iran.

6 Cancer Molecular Pathology Research Center, Mashhad University of Medical Science, Mashhad, Iran

7 Resident of Pathology, Cancer Molecular Pathology Research Center, Mashhad University of Medical Science, Mashhad, Iran.

8 Department of Hematology, School of Allied Medical Sciences, IRAN University of Medical Sciences, Tehran, IRAN.

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چکیده

Background: Bone marrow transplantation (BMT) is considered as a curative therapy for a broad range of diseases. However, complications such as relapse and graft versus host disease (GVHD) may be observed following BMT. Chimerism analysis serves as a reliable indicator of transplant outcome. Complete chimerism refers to the complete replacement of hematopoietic system ...