Indirect Molecular Diagnosis of Congenital Factor ΧІІІ Deficiency by Candidate Microsatellites and Single Nucleotide Polymorphisms
نویسندگان
1 Department of Medical Biotechnology, School of Allied Medicine, Iran University of Medical Sciences. Tehran- Iran
2 Department of Medical Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
3 Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
4 Department of Medical Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5 Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
6 Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
7 Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
8 Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, Iran
9 Department of laboratory sciences, School of Allied Medicine, Arak University of Medical Sciences, Arak, Iran
doi
چکیده
Background: Congenital factor XIII (FXIII) deficiency is one of the rarest bleeding disorders with a prevalence of one per 2 million in the general population. The disorder is accompanied by a high rate of life-threatening bleeding. Due to normal results of routine coagulation tests, diagnosis of the disorder is challenging, but molecular methods ...
