Overexpression of the IL-33/ST2 in Pediatric Acute Lymphoblastic Leukemia: Evaluation of the Effects of a Treatment Program
نویسندگان
1 Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran - Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
2 Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran - Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3 Department of Immunology, Medical School, Kerman University of Medical Sciences, Kerman, Iran - Department of Immunology, Medical School, Kerman University of Medical Sciences, Kerman, Iran
4 Department of Hematology and Laboratory Sciences, Para-Medicine School, Kerman University of Medical Sciences, Kerman, Iran - Department of Hematology and Laboratory Sciences, Para-Medicine School, Kerman University of Medical Sciences, Kerman, Iran
doi
10.18502/ijpho.v15i3.18920چکیده
Background: The study focuses on B-acute lymphoblastic leukemia (B-ALL), a common childhood blood cancer marked by an overproduction of B lymphocytes. It explores the role of cytokine expression changes, particularly Interleukin-33 (IL-33), which has both anti- and pro-tumor effects. The research assesses the expression of IL-33 and its receptor, suppression of tumorigenicity ...
