The Efficacy of Toll-Like Receptors in Awakening Dendritic Cell/Natural Killer Cell System for Eradication of Tumors

نویسندگان
Yazdani Elahabad, Parisa i ID 1
Hekmatimoghaddam , Seyedhossein ID 2
Pourrajab , Fatemeh ID 3

1 School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Hematology and Oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

3 Department of Biochemistry and Molecular Biology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

doi
چکیده

Natural killer (NK) cells are effector cells of the innate immune system that exert direct cytotoxic functions. Ubiquitously-expressed toll-like receptors (TLRs) have been recognized as one of the major components promoting dendritic cell (DC) maturation, which may induce polarized immune responses beneficial to cancer immunotherapy. TLR-activated NK cells and DCs ...

کلیدواژه‌ها
Dendritic Cell, Immune System, Natural Killer Cell, Toll-like Receptor, Tumor