Assessment of Liver and Kidney Functional Parameters along with Oxidative Stress and Inflammatory Biomarker in Patients with β- Thalassemia Major

نویسندگان

1 Department of medical laboratory sciences, school of allied medical sciences, shahid Beheshti University of medical sciences, Tehran, Iran

2 Department of pathology, School of medicine, Kashan University of Medical Sciences, Kashan, Iran

3 Hematology-Oncology and Stem cell Transplantation Research Center, Tehran university of Medical Science, Tehran, Iran

4 Department of Medical Laboratory Sciences, Faculty of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, Iran

5 Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran

6 Metabolic Disorders Research Center, Department of biochemistry, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran

7 Department of Epidemiology, Faculty of Public Health, Ilam University of Medical Sciences, Ilam, Iran7. Metabolic Disorders Research Center, Department of biochemistry, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran

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چکیده

Abstract Background: Thalassemias are the most common inherited blood disorders caused by some mutations which can reduce the synthesis of globin chains. Iron overload and its organ deposition are responsible for functional abnormalities and tissue injury in patients who affected by β-thalassemia major. The aim of this case-control study was ...