Quantitative Assessment of WT1 Expression by Real Time Quantitative PCR in Pediatric Patients with Acute Myeloblastic Leukemia

نویسندگان
Ayatollahi, Hossein ID 1
sadeghian, Mohammad hadi ID 2
Sheikhi, Maryam ID 3
Alidadi, Mohammad ID 4
Bahrami, Afsane ID 5
Shakeri, Sepideh ID 6
Shams, Seyyede Fatemeh ID 7
Motamedi rad, Neda ID 8

1 Department of Hematology and Blood Bank, Faculty of Medicine, Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Department of Hematology and Blood Bank, Faculty of Medicine, Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

4 Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

5 Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

6 Department of Hematology and Blood Bank, Faculty of Medicine, Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

7 Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

8 Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

doi
چکیده

Background: Acute myeloid leukemia (AML) is one of myeloid malignancies which the risk increases with age increment. It is categorized based on genetic aberrations. Some of these genetic disorders can determine minimal residual diseases (MRD) and prognosis of AML patients. Wilms tumor (WT1) over expression is found in AML patients. ...

کلیدواژه‌ها
Acute myeloid leukemia pediatrics, Quantitative reverses transcription PCR, Wilms tumor