Analysis and Identification of Rare and Prevalent Breakpoints in Chromosomal rearrangements in Adult and Pediatric with B-Acute Lymphoblastic Leukemia (B-ALL): A Systematic Review
نویسندگان
1 Department of Biology, Yazd University, Yazd, Iran - Department of Biology, Yazd University, Yazd, Iran
2 Department of Biology, Yazd University, Yazd, Iran - Department of Biology, Yazd University, Yazd, Iran
3 Department of Biology, Yazd University, Yazd, Iran - Department of Biology, Yazd University, Yazd, Iran
4 Department of Biology, Yazd University, Yazd, Iran - Department of Biology, Yazd University, Yazd, Iran
doi
10.18502/ijpho.v14i3.15992چکیده
Background: B-cell acute lymphoblastic leukemia (B-ALL) is a complex disorder that includes multiple genetic changes, one of the main causes of which is rare and common chromosomal translocations that lead to abnormal gene fusions. This abnormal fusion produces a new protein that causes the leukemia cells. These types of rearrangements usually occur ...
