Analysis of BAALC gene Expression as prognosis factor in Pediatric Acute Myeloid Leukemia in Iran
نویسندگان
1 Cancer Molecular pathology Research center, Department of Hematopathology and blood banking, Faculty of Medicine, Ghaem Hospital, Mashhad university of Medical sciences, Mashhad, Iran.
2 MSc. Cancer Molecular Pathology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 MSc. Cancer Molecular Pathology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Cancer Molecular pathology Research center, Ghaem Hospital, Mashhad university of Medical sciences, Mashhad, Iran.
5 Cancer Molecular pathology Research center, Ghaem Hospital, Mashhad university of Medical sciences, Mashhad, Iran
6 MSc of hematology and blood banking, Mashhad University of medical sciences, Mashhad, Iran.
7 Cancer Molecular pathology Research center, Department of Hematopathology and blood banking, Faculty of Medicine, Ghaem Hospital, Mashhad university of Medical sciences, Mashhad, Iran.
8 MSc. Cancer Molecular Pathology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
9 MSc. Cancer Molecular Pathology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
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چکیده
Background:Brain and Acute Leukemia Cytoplasmic (BAALC) is a gene which its expression is confined to progenitor cells; therefore, no expression has been illustrated in mature cells of bone marrow or white blood cells (WBC). In addition, high BAALC expression is associated with poor prognosis in Acute Myeloid Leukemia (AML) individuals and ...