Evaluating the Effects of Chemotherapy Drugs and Thiosemicarbazone Complexes on the Alteration of SNHG16 Expression in Acute Lymphoblastic Leukemia

نویسندگان
Erfanipour, Fatemeh ID 1
Asaadi Tehrani, Golnaz ID 2
Ghorbani, Fatemeh ID 3
Mirzaahmadi , Sina ID 4

1 Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan, Iran

2 Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan, Iran.

3 Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan, Iran

4 Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan, Iran

doi
10.18502/ijpho.v13i3.13130
چکیده

Background: Acute lymphoblastic leukemia (ALL) is a malignant disease that afflicts both children and adults. It starts from the bone marrow (soft and spongy tissue inside the bone) where immature white blood cells or lymphocytes are formed. This study aims to compare chemotherapy drugs, methotrexate (MTX), cyclophosphamide, cytarabine (Ara-C) and mercaptopurine ...

کلیدواژه‌ها
Acute lymphoblastic leukemia, Chemotherapy, Drugs, Long noncoding RNA