Efficient Production of Platelets from Umbilical Cord Blood Stem Cells Using A Collagen-Tragacanth Scaffold in A Multi-Chamber Bioreactor

نویسندگان
Baradar khoshfetrat, Ali ID 1
Sanaat, Zohre ID 2
Nozad Charoudeh, Hojjatollah ID 3
Derakhty Gonbad, Mohamad Hosein ID 4
Movassaghpour, Ali Akbar ID 5

1 Chemical Engineering Faculty, Sahand university of Technology, Tabriz, Iran

2 Department of Hematology and Oncology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

3 Drug applied Research Center, Tabriz university of Medical Sciences, Tabriz, Iran

4 Applied Cell Sciences Department, Advanced Research Medical School, Tabriz University of Medical Sciences, Tabriz, Iran

5 Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

doi
10.18502/ijpho.v13i3.13131
چکیده

Background: To date, platelet (PLT) transfusion is the main medical option for the treatment of thrombocytopenia. Nowadays, allogenic PLTs are commonly used for blood donation. Due to the limitations in the preparation and storage of PLTs, researchers try to develop alternative modalities such as bioreactors for the in-vitro expansion and ...

کلیدواژه‌ها
Bioreactor, Megakaryocyte, Platelet, Scaffold, Tragacanth