Transcriptomic Profiling of Pediatric Acute Lymphoblastic Leukemia Subtypes Identifies Novel Prognostic Markers
نویسندگان
1 College of Science, University of Tikrit, Tikrit, Iraq - College of Science, University of Tikrit, Tikrit, Iraq
2 Department of Biotechnology, College of Science, University of Anbar, Ramadi, Anbar, Iraq - Department of Biotechnology, College of Science, University of Anbar, Ramadi, Anbar, Iraq
3 Salahadeen general hospital, ministry of Health, Tikrit, Iraq - Salahadeen general hospital, ministry of Health, Tikrit, Iraq
4 College of Science, University of Tikrit, Tikrit, Iraq - College of Science, University of Tikrit, Tikrit, Iraq
doi
10.18502/ijpho.v16i1.20422چکیده
Background: Pediatric acute lymphoblastic leukemia (ALL) encompasses more than 20 molecular subtypes with diverse genetic and prognostic profiles. The 11q subtype, characterized by KMT2A rearrangements, exhibits an aggressive clinical course compared with favorable subtypes such as high hyperdiploidy (HeH) and dic (9; 20). This study aimed to elucidate the distinct ...
