Evaluation of Chelidonium Majus L. Alkaloid Effect on VEGF Gene Expression and Cell Apoptosis in the Burkitt Lymphoma Cell Line

نویسندگان

1 Department of Microbiology Faculty of Biological Sciences, Islamic Azad University, North Tehran branch, Tehran, Iran - Department of Microbiology Faculty of Biological Sciences, Islamic Azad University, North Tehran branch, Tehran, Iran

2 Associate professor, Department of Microbiology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran - Medical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

3 Assistant professor, Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University, North Tehran branch, Tehran, Iran - Assistant professor, Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University, North Tehran branch, Tehran, Iran

4 Assistant professor, Department of Arboviruses and Viral Hemorrhagic Fevers (National Ref Lab), Pasteur Institute of Iran, Tehran, Iran - Assistant professor, Department of Arboviruses and Viral Hemorrhagic Fevers (National Ref Lab), Pasteur Institute of Iran, Tehran, Iran

doi
10.18502/ijpho.v15i1.17280
چکیده

Background: Burkitt lymphoma (BL) is a type of mature B-cell non-Hodgkin’s lymphoma that commonly develops in children and young adults. Vascular endothelial growth factor (VEGF) is acknowledged as a vital regulator of angiogenesis in both normal and disease states. In light of the adverse effects linked to chemical treatments, this study aimed ...