Current understanding in diagnosis and management of factor XIII deficiency

نویسندگان
Dorgalaleh , A ID 1
Alizadeh , Sh ID 2
Eshghi , P ID 3
Naderi , M ID 4
Tabibian , Sh ID 5
Solaimani , Gh ID 6

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چکیده

Factor XIII or "fibrin-stabilizing factor," is a transglutaminase circulates in the blood circulation as a hetero tetramer with two catalytic A subunits and two carrier B subunits. This important coagulation factor has a crucial role in clotting cascade and produces strong covalent bonds between soluble formed fibrin monomers during coagulation. This stable cross linked fibrin ...

کلیدواژه‌ها
Factor XIII; Coagulation; Bleeding