Effect of Estradiol on miR-21& miR-155 Expression in promyelocytic leukemia-derived cell line NB4

نویسندگان
Khamisipour, Gholamreza ID 1
Naghibzadeh, Robab ID 2
Obeidi, Narges ID 3
Farsinejd, Alireza ID 4
Tohid Far, Masoud ID 5

1 Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.

2 Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

3 Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

4 Department of Hematology and Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Kerman University of Medical Sciences, Kerman, Iran

5 Department of Hematology and Medical Laboratory Sciences, Faculty of Allied Medical Sciences, ShahidBeheshti University of Medical Sciences, Tehran, Iran

doi
10.18502/ijpho.v10i1.2169
چکیده

Background: Due to the estrogen participation in modulating the proliferation and commitment of stem cells and the effects of miR-21 and miR-155 expression on reduced proliferation and colony formation of acute myeloid leukemia (AML), the aim of the present study was to evaluate the effect of estradiol on expression of ...

کلیدواژه‌ها
cute Myeloid Leukemia (AML), Estradiol, MiR-155, MiR-21