Frequency Determination of c.1115_1118delTTGG and c.3788_3790delTCT FANCA Gene Mutation in North of Khyber Pakhtunkhwa (KPK) Pakistan Fanconi’s Anemia Population

نویسندگان
Khan, Adnan ID 1
Masood, Tariq ID 2
Ayaz, Maaz ID 3
Ayaz, Kinza ID 4
Arabdin, Maria ID 5
Sohail Taj, Abid ID 6

1 Rehman Medical Institute, Peshawar, Pakistan

2 North West School of medicine, Peshawar, Pakistan

3 Queen Mary university of London, London, England

4 Khyber Medical University

5 Rehman Medical Institute, Peshawar, Pakistan

6 Khyber Medical University, Peshawar, Pakistan

doi
10.18502/ijpho.v12i3.10059
چکیده

Background: This study aimed to assess the frequency determination of c.1115_1118delTTGG and c.3788_3790delTCT Fanconi's anemia A gene (FANCA) gene mutation in the North of Khyber Pakhtunkhwa (KPK) Pakistan Fanconi’s Anemia Population. Materials and Methods: A cross-sectional study was conducted at Khyber Medical University, Peshawar, Pakistan. For the Exon 13 mutation c.1115_1118delTTGG, the ...

کلیدواژه‌ها
Aplastic anemia, Complementation group A protein, Fanconi anemia, Polymerase chain reaction, Single nucleotide polymorphism