The Effectiveness of N-acetylcysteine in Preventing Oral Mucositis Induced by Chemotherapy among Children with Cancer: A Double-Blind Randomized Controlled Trial

نویسندگان

1 Thalassemia & Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran - Thalassemia & Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Department of Pediatrics, Air Pollution and Respiratory Diseases Research Center, Abouzar Hospital, School of Medicine, Ahvaz Jundishapur University of Medical Sciences Ahvaz, Iran. - Clinical Pharmacy Department, Faculty Of Pharmacy, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran

3 Clinical Pharmacy Department ,Faculty Of Pharmacy, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran. - Clinical Pharmacy Department, Faculty Of Pharmacy, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran

4 Thalassemia & Hemoglobinopathy Research Center, Health Research Institute, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran - Clinical Pharmacy Department, Faculty Of Pharmacy, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran

5 Student Research Committee, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. - Student Research Committee, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

6 Student Research Committee, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. - Student Research Committee, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

7 Clinical Pharmacy Department ,Faculty Of Pharmacy, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran. - Thalassemia & Hemoglobinopathy Research Center, Health Research Institute, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran

8 Clinical Pharmacy Department ,Faculty Of Pharmacy, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran. - Department of Pediatrics, Air Pollution and Respiratory Diseases Research Center, Abouzar Hospital, School of Medicine, Ahvaz Jundishapur University of Medical Sciences Ahvaz, Iran

doi
10.18502/ijpho.v16i3.21748
چکیده

Background: Oral mucositis (OM) is a common chemotherapy complication in children, linked to oxidative stress. The aim of the study was to evaluate the efficacy of oral N-acetylcysteine (NAC) compared to placebo in children with malignancy at risk of mucositis induced by chemotherapy. Materials and Methods: The double-blind randomized controlled trial ...