Spleen-Saving or Spleen-Sacrificing? Rethinking Splenectomy Strategies in Thalassemia
نویسندگان
1 Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran - Associate professor, Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Pediatric Surgery, Shiraz University of Medical Sciences, Shiraz, Iran - Professor, Department of Pediatric Surgery, Shiraz University of Medical Sciences, Shiraz, Iran
3 Bushehr University of Medical Sciences, Bushehr, Iran - Associate professor of pediatric hematology and oncology, Bushehr University of Medical Sciences, Bushehr, Iran
4 Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran - Professor of pediatric hematology and oncology, Shiraz University of Medical Sciences, Shiraz, Iran
5 Department of Pediatric Surgery, Shiraz University of Medical Sciences, Shiraz, Iran - Professor of pediatric surgery, Shiraz University of Medical Sciences, Shiraz, Iran
6 Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran - Assistant professor of pediatric hematology and oncology, Shiraz University of Medical Sciences, Shiraz, Iran
doi
10.18502/ijpho.v16i3.21752چکیده
Background: Splenomegaly and hypersplenism are common complications in thalassemia that may require splenectomy. Although total splenectomy (TS) effectively improves hematologic parameters, it is associated with increased risks of infection and thrombosis. Partial splenectomy (PS) has been proposed as a spleen-preserving alternative to reduce these complications. This study compares the clinical outcomes ...