Assessment of acute kidney injury by urinary β2-MG and NAG in pediatric cancer patients prescribed with Cisplatin, Carboplatin, and Ifosfamide as the chemotherapeutic agents
نویسندگان
1 Department of Pediatric Hematology-Oncology, Isfahan University of Medical Sciences, Isfahan, Iran.
2 Division of Genetics, Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.
3 Isfahan University of Medical Sciences, Isfahan, Iran.
4 Department of Pediatric Hematology-Oncology, Isfahan University of Medical Sciences, Isfahan, Iran.
5 Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran.
6 Department of Pediatric Nephrology, Isfahan University of Medical Sciences, Isfahan, Iran.
doi
10.18502/ijpho.v10i4.4404چکیده
Background: Acute kidney injury (AKI) is defined as a failure in renal function leading to insufficiency of fluid and electrolyte homeostasis. Thus, sensitive biomarkers of renal tubular injury are needed to detect AKI earlier. In this study, urinary beta 2-microglobulin (β2-MG) and urinary N-acetyl-β-D-glucosaminidase (NAG) were evaluated for AKI prognosis/diagnosis in ...
