Effect of Curcumin and Trichostatin A on the Expression of DNA Methyltransfrase 1 in Hepatocellular Carcinoma Cell Line Hepa 1-6

نویسندگان
Sanaei, Masumeh ID 1
Kavoosi, Fraidoon ID 2

1 Research Center for Non-communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran

2 Research Center for Non-communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran

doi
چکیده

Background: Hepatocellular carcinoma (HCC), primary liver cancer, is a major health problem and the third most common cause of cancer-related deaths worldwide. Epigenetic modulations are essential for the maintenance of gene expression patterns in mammals. Disruption of these processes can lead to silenced gene and malignant cellular transformation. The current study ...

کلیدواژه‌ها
Apoptosis, Curcumin, DNMT1, Trichostatin