Investigating the Immunological Significance of TGFB1 and MDA in ALL TME

نویسندگان

1 Universitas Prima Indonesia - Universitas Prima Indonesia

2 Universitas Prima Indonesia - Universitas Prima Indonesia

3 Universitas Prima Indonesia - Universitas Prima Indonesia

doi
10.18502/ijpho.v15i4.19629
چکیده

Background: The tumor microenvironment (TME) in acute lymphoblastic leukemia (ALL) significantly shapes disease progression and therapeutic responses. This study investigates the regulatory role of bone marrow mesenchymal stem cell (BMSC)-released transforming growth factor beta-induced factor homeobox 1 (TGIF1) on myeloid nuclear differentiation antigen (MNDA) expression, immune infiltration, and patient prognosis in ...