Challenges and Developments in Prenatal Diagnosis of Beta-Thalassemia: A Study on Diagnostic Accuracy

نویسندگان
Keikhaei, Bijan ID 1
Kalantarfard, Nozar ID 2
Mahmoudian-Sani, Mohammad Reza ID 3

1 Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran - Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran - Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran - Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

doi
10.18502/ijpho.v15i4.19631
چکیده

Background: Beta-thalassemia major is prevalent in areas like Khuzestan, Iran, and causes severe anemia requiring lifelong treatment. Despite successful prevention programs, diagnostic errors in Prenatal Diagnosis (PND) persist, leading to affected births. This study evaluates the accuracy of PND, identifies the causes of errors, and suggests improvements to diagnostic protocols. ...

کلیدواژه‌ها
Beta-Thalassemia, Chorionic Villus Sampling, Diagnostic Error, Mutation, Prenatal Diagnosis