Enhancing Platelet Preservation through Freeze-Drying and Sterilization: An Approach for the Improvement of Hemostatic Treatment and Platelet Concentrate Supply
نویسندگان
1 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran - Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2 Biological Products and Blood Safety Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran - Biological Products and Blood Safety Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
3 Biological Products and Blood Safety Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran - Biological Products and Blood Safety Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
4 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran - Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
doi
10.18502/ijpho.v15i2.18176چکیده
Background: The limited shelf life of platelets has led to an increasing demand for longer-lasting products. This study aimed to develop a lyophilization protocol to preserve platelets by using trehalose, a desiccation-resistant sugar, and comparing its effectiveness to sucrose, a standard sugar for protein lyophilization. Materials and Methods: In this interventional study, the ...
