The Role of Autophagy-Associated Genes in the Pathogenesis of Patients with Acute Lymphoblastic Leukemia

نویسندگان

1 Non-Communicable Diseases Research Center, Department of Immunology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran - Non-Communicable Diseases Research Center, Department of Immunology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran

2 Department of Laboratory Sciences, School of Allied Medical Sciences, Alborz University of Medical Sciences, Karaj, Iran - Department of Laboratory Sciences, School of Allied Medical Sciences, Alborz University of Medical Sciences, Karaj, Iran

3 Department of Laboratory Sciences, School of Allied Medical Sciences, Guilan University of Medical Sciences, Rasht, Iran - Department of Laboratory Sciences, School of Allied Medical Sciences, Guilan University of Medical Sciences, Rasht, Iran

doi
10.18502/ijpho.v15i2.18177
چکیده

Background: Expanding the knowledge of the underlying molecular mechanisms in acute lymphoblastic leukemia (ALL) is of great importance to improving treatment outcomes. Autophagy, a critical and evolutionarily conserved pathway, plays an important role in maintaining cellular homeostasis under stressful conditions. This pathway consists of several sequential steps. The present study aimed ...