Pediatric Buccal Epigenetic (PedBE) and Neonatal Epigenetic Estimator of Age (NEOage) Clocks: A Focus on Pediatric Oncology

نویسندگان

1 Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran - Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran

3 Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran - Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

4 Department of Obstetrics and Gynecology, Iranshahr University of Medical Sciences, Iranshahr, Iran - Department of Obstetrics and Gynecology, Iranshahr University of Medical Sciences, Iranshahr, Iran

5 Department of Cancer Biology, College of Medicine, University of Cincinnati, Ohio, USA - Department of Cancer Biology, College of Medicine, University of Cincinnati, Ohio, USA

6 Department of Radiology, Shahid Rahnamoun Hospital, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - Department of Radiology, Shahid Rahnamoun Hospital, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

7 Department of Radiology, Shahid Rahnamoun Hospital, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - Department of Radiology, Shahid Rahnamoun Hospital, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

8 Hematology and Oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - Hematology and Oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

9 Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran - Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

10 Department of Pediatrics, Islamic Azad University of Yazd, Yazd, Iran - Department of Pediatrics, Islamic Azad University of Yazd, Yazd, Iran

11 Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Tehran, Iran - Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Tehran, Iran

12 Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

13 Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran - Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

14 Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

doi
10.18502/ijpho.v15i2.18178
چکیده

The Pediatric Buccal Epigenetic (PedBE) and Neonatal Epigenetic Estimator of Age (NEOage) clocks provide a novel method for assessing the biological age of young individuals, enhancing our comprehension of their health and development. By analyzing DNA methylation patterns, these clocks identify risk factors for various health conditions and guide personalized interventions ...