A Randomized, Controlled Study Evaluating the Effects of Silymarin Addition to Deferasirox on the Liver Function of Children with Transfusion-Dependent Thalassemia
نویسندگان
1 Department of Pediatrics, Arak University of Medical Sciences, Arak, Iran
2 School of Medicine, Iran University of Medical Sciences, Tehran, Iran
3 Department of Pediatrics, Erfan Niyayesh Hospital, Tehran, Iran
4 Cancer Research Center, Semnan University of Medical Sciences, Semnan, Iran
5 Department of Pediatrics, Aliasghar Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran
6 Department of Pediatrics, Arak University of Medical Sciences, Arak, Iran
doi
10.18502/ijpho.v11i4.7169چکیده
Background: Frequent blood transfusion can lead to iron overload which is potentially dangerous for the heart and liver. Silymarin has well-documented protective effects on hepatocytes. The purpose of this study was to evaluate the hepatoprotective effects of silymarin addition to iron chelators in children with thalassemia. Materials and Methods: This ...
