Red Blood Cells Alloimmunization and Autoimmunization in Multi-transfused Thalassemia Patients in South of Iran

نویسندگان

1 MSc student of Hematology & Blood Banking, Department of Hematology and Blood Bank

2 Cancer molecular pathology research center, Emam Reza hospital

3 Cancer molecular pathology research center, Emam Reza hospital

4 MSc of immunology

5 Faculty of Medicine

doi
10.18502/ijpho.v9i1.295
چکیده

Background: Recurrent blood transfusion is a common treatment in patients with thalassemia. The development of antibodies against red blood cell (RBC) antigens complicates RBC cross-matching, enhances the in vivo destruction of transfused cells, accelerates tissue iron overloading, delays the provision of safe transfusion, and reduces health-related quality of life. Materials and ...