The Relationship between Mutation in HOXB1 Gene and Acute Myeloid Leukemia

نویسندگان
Vahidi mehrjardi, Mohammad yahya ID 1
Aghaei Zarch , Seyed Mohsen ID 2
Dehghani, Mohammadreza ID 3

1 Department of Genetic, ShahidSadoughi University of Medical Sciences, Yazd, Iran

2 Department of Genetic, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

3 Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

doi
10.18502/ijpho.v9i4.1571
چکیده

Background: HOX genes are an exceedingly preserved family of homeodomain-involving transcription factors. They are related to a number of malignancies, comprising acute myeloid leukemia (AML). This study aimed to evaluate the effect of HOXB1 7bp deletion mutation on HOXB1gene expression in 36 individuals. Materials and Methods: The present cross-sectional study was ...

کلیدواژه‌ها
Acute Myeloid Leukemia, Gene expression, HOXB1