Clinical and Laboratory Findings of Cup-Like Nuclei in Blasts with FLT3 Mutation in Pediatric Acute Myeloid Leukemia: A Case Report

نویسندگان
Fe Joibi, Kimberly ID 1
Shafii, Nor Fadhilah ID 2
Mustaffa, Rapiaah ID 3
Wan Abdullah, Wan Zaidah ID 4
Ibrahim, Salfarina ID 5
Mat Jusoh , Siti Asmaa ID 6
Johan, Muhammad Farid ID 7

1 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia

2 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia

3 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia

4 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia

5 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia

6 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.

7 Department of Hematology & Transfusion Medicine Unit, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia

doi
10.18502/ijpho.v9i4.1577
چکیده

Biologically, Acute myeloid leukemia (AML) is highly heterogenous. AML with cup-like blast morphology variant has been reported to have important role in risk group stratification and treatment implications. In pediatric age group, this morphology and its clinical implication is rarely discussed. Although this morphology variant is not stated in World ...

کلیدواژه‌ها
Acute myeloid leukemia, Blast, FLT3, Mutation