Overexpression of microRNA-630 in Acute Leukemic T-cell line

نویسندگان
Gharehdaghi, Zeynab ID 1
Khamisipour, Gholamreza ID 2
Obeidi, Narges ID 3
Rostami yasuj, Shagayegh ID 4

1 Blood Transfusion Organization, Bushehr, Iran

2 Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.

3 Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

4 Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

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چکیده

Background: MicroRNAs (miRNAs) are noncoding RNAs that control the expression of their target mRNAs. It affects cancer cell proliferation and apoptosis as oncogenes or tumor suppressors. Dysregulation of miRNAs expression leads to the development of various cancers. Therefore, for the first time in this field, this study investigated the effect ...

کلیدواژه‌ها
Acute Lymphoblastic Leukemia, MiR-630, Overexpression, p53 Genes