The Effect of Chitosan and Chitin Oligomers on Gene Expression and Lignans Production in Linum album Cell Cultures

نویسندگان
Satake, H ID 1
Esmaeilzadeh Bahabadi, S ID 2
Sharifi, M ID 3
Murata, J ID 4

1 Suntory Foundation for Life Sciences, Bioorganic Research Institute, Osaka, Japan

2 Department of Biology, Faculty of Basic Sciences, University of Zabol, Zabol, Iran

3 Department of Plant Biology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran

4 Suntory Foundation for Life Sciences, Bioorganic Research Institute, Osaka, Japan

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چکیده

Background: Linum album, a herbaceous and medicinal plant, has been shown to accumulate anti-tumor podophyllotoxin (PTOX) and related lignans. Objective: In this study, we have verified the time-course of cell growth, lignan production in cells treated with chitosan and chitin oligomers. To study mechanism of chitosan and chitin oligomers action, expression ...

کلیدواژه‌ها
Linum album, Chitosan oligomers, Gene expression, Podophyllotoxin