Over - expression Effect of Gene Encoding 3-hydroxy-3-Methylglutaryl-CoA Reductase on Production of Taxol in Iranian Hazel (Corylus avellana L.)
نویسندگان
1 Department of Plant Breeding, Science and Research Branch, Islamic Azad University
2 Department of Agronomy and Plant Breeding, Faculty of Agriculture, Tehran University
3 Agronomy and Plant Breeding Department, Faculty of Agriculture, Razi University
4 Pharmacognosy & Pharmaceutics Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR
doi
چکیده
Background: Sustainable and commercial production of taxol as an anti cancer drug is a critical point to its clinical application. Nowadays, hazel because of rapid growth and wide range distribution is considered as an alternative source of Taxol. Objective: To increase taxol production the cDNA encoding 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) from Iranian ...