Anti-hyperglycemic Effects of Saffron and its Active Constituents, Crocin and Safranal, in Alloxan-Induced Diabetic Rats

نویسندگان

1 Department of Pharmacology and Applied Medicine, Institute of Medicinal Plants, ACECR

2 Department of Pharmacognosy and Pharmaceutics, Institute of Medicinal Plants, ACECR

doi
چکیده

Background: Saffron is the dried stigmata of the flowers of saffron (Crocus sativus L., Iridaceae). Saffron and its major active constituents, crocin (crocetin glycoside), crocetin and safranal, have a variety of pharmacological effects including high antioxidant properties and crocetin has insulin sensitizing effect possibly due to its antioxidant activity. Oral crocin ...