Effects of Rosa damascena (Damask rose) on menstruation‑related pain, headache, fatigue, anxiety, and bloating: A systematic review and meta‑analysis of randomized controlled trials
نویسندگان
1 Department of Community Health Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Student Research Committee, Department of Operating Room Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
3 Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Medical Science, Tehran, Iran
4
doi
چکیده
Recent studies have reported inconclusive results regarding the therapeutic effects of Rosadamascena on the outcomes of primary dysmenorrhea (PD) and premenstrual syndrome (PMS).Hence, this study is aimed to summarize the findings of randomized controlled trials (RCTs)regarding the effects of this treatment on menstruation‑related pain as the primary outcome andmenstruation‑related headache, fatigue, anxiety, and bloating as the secondary outcomes. Thisstudy evaluated parallel‑group and cross‑over RCTs on aromatherapy, topical treatment, ororal intake of R. damascena products for the treatment groups versus placebo, nontreated, orconventional treatment groups. Seven electronic databases (Web of Science Core Collection,Scopus, Embase, CENTRAL, CINAHL, SID, and MagIran) and one search engine (PubMed) weresearched from inception to January 15, 2021. Of 1468 trials found in the initial search, 983 potentiallyrelevant articles were screened by title and abstract. After examining the full‑text of 13 studies forcompliance with the inclusion criteria, seven studies were considered eligible for this review. Arandom‑effects model was used to pool the data; otherwise, a narrative summary was presented.The retrieved studies were conducted on females with PD or PMS, aged 18–35 years. The totalsample size of the intervention and comparator arms was 276 and 272. The results showed thatR. damascena had a nonsignificant alleviating effect on the menstruation‑related pain (weightedmean difference [WMD]: −0.47; 95% confidence interval [CI]: −1.25, 0.31; P = 0.234). Such findingswere also found for menstruation‑related anxiety (WMD: −0.40; 95% CI: −0.91, 0.11; P = 0.125).However, the treatment significantly reduced the menstruation‑related headache (WMD: −0.42;95% CI: −0.74, −0.11; P = 0.008), fatigue (WMD: −0.48; 95% CI: −0.87, −0.09; P = 0.015), andbloating (WMD: −0.72; 95% CI: −1.21, −0.22; P = 0.005). Since R. damascena had no significanteffects on menstruation‑related pain and anxiety, further studies with improved methodologicalquality are suggested to evaluate the effects of the treatment on these symptoms, using differentdosages and durations.
