A Mini-review on Aging and Its Impact on Bone Health
نویسندگان
1 Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Shafayahyaeian Hospital, Iran University of Medical Sciences, Tehran, Iran.
2 Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.
3 Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Shafayahyaeian Hospital, Iran University of Medical Sciences, Tehran, Iran.
4 Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Shafayahyaeian Hospital, Iran University of Medical Sciences, Tehran, Iran.
5 Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Shafayahyaeian Hospital, Iran University of Medical Sciences, Tehran, Iran.
doi
10.32598/JROSJ.11.2.1801.2چکیده
Aging significantly impacts bone health, resulting in changes to bone composition, structure, and function. Bone remodeling, a dynamic process involving osteoclast-mediated resorption and osteoblast-mediated formation, is crucial for maintaining skeletal integrity and adapting to physiological demands. In youth, bone turnover is balanced, but with aging, this equilibrium is disrupted, leading to ...