The Fruit Essential oil of Cuminum cyminum L. Reduced the Acquisition but not Expression of Ineffective dose of Morphine-Induced Conditioned Place Preference in Morphine- Sensitized Mice

نویسندگان

1 Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran

2 Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran

3 Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran

4 Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran

5 Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran

doi
چکیده

Background: Cuminum cyminum fruit essential oil (FEO) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice. Objective: In this study, the effects of Cuminum cyminum FEO on acquisition and expression of morphine-induced conditioned place preference (CPP) in morphine-sensitized mice were studied. Methods: Repeated subcutaneous (s.c.) administration ...