Do Antibiotic Beads Need to be Removed?
نویسندگان
1 Hip and Knee Center at Northwest Primary and Specialty Care North Seattle, University of Washington, Seattle, WA, USA
2 Aurora Medical Center Summit Oconomowoc, WI, USA
3 Department of Orthopedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA
4 Department of Orthopedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA
5 Department of Orthopedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA
doi
10.22038/abjs.2020.44143.2208چکیده
Background: Polymethylmethacrylate antibiotic impregnated beads can be an effective treatment for chronicosteomyelitis or an adjuvant in the treatment of open fractures. It remains unclear however whether the beads causelong-term adverse events if not removed. The purpose of this study was to determine if removal of antibiotic beads wasrequired in order to avoid long term complications.Methods: A retrospective chart review was conducted on patients with an extremity or pelvis fracture that hadimplantation of polymethylmethacrylate (PMMA) antibiotic beads over a five-year period.Results: Fifty-one patients met inclusion criteria for this study; thirty-seven patients (73%) did not have complicationsafter surgical debridement and placement of PMMA antibiotic beads necessitating removal.Conclusion: Our findings suggest that polymethylmethacrylate antibiotic beads can be utilized as a means of deliveringhigh-dose concentrations of local antibiotics and do not have to be removed in all patients.Level of evidence: III
